The USE (Ultrasound Enhancement) project primarily seeks to bring out a breakthrough in ultrasound-guided interventions during breast, liver, thyroid and lymph node-related surgical procedures. To that end, 2D and 3D measurements providing anatomical (B-mode ultrasound) and mechanical stiffness (elastrography and acoustic radiation force impulse imaging) information are investigated and combined, in order to enable the detection of very small tumors (less than 2 mm). Within the project, a clinical ultrasound transducer (Automated Breast Volume Scanner (ABVS)) will be integrated reconstruct the organ shape, and detect the tumors.